Research projects

We help to progress high-quality translational research across our theme areas, addressing the most pressing health issues for our communities

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Showing 29 research projects

Mind The Gap: Steps towards precision rehabilitation in chronic pain

Rehabilitation

Using VR technology to understand the neurobiological mechanisms of chronic pain to develop effective treatments

Evaluating the efficacy of a zinc-gel in preventing recurrent vulvovaginal candidiasis

Clinical mycology

Establishing the role of fungal infection in potentiating Alzheimer’s Disease risk

Clinical mycology

Neurodegeneration

Understanding possible triggers of Alzheimer’s Disease to help improve treatments

Knee4Life: Empowering Knee Recovery After Total Knee Replacement Through Digital Health

Rehabilitation

Creating a tool for early detection of pain and stiffness which occurs in the recovery phase of up to 20% of total knee replacement patients

Releasing a critical bottleneck in Pneumocystis research

Clinical mycology

Using an innovative approach to progress research into a deadly human pathogen and develop new treatments

Developing novel screening strategies to identify modulators of microglial cell states

Neurodegeneration

Understanding the brain’s immune cells to help develop treatments for people with Alzheimer’s disease.

Using whole genome sequencing to identify non-coding elements associated with common, complex phenotypes

Genetics and Genomics

Understanding the role in disease development of the non-coding genome to help improve treatments

Analysis of extracellular vesicle cargo as biomarkers to differentiate Alzheimer’s disease and dementia with Lewy bodies

Neurodegeneration

Understanding and tracking changes in the brain during neurodegeneration to help improve treatments

Investigating the aetiology of non-autoimmune young-onset diabetes in sub-Saharan Africa.

Diabetes

Understanding the causes of an unusual form of diabetes in young people in sub-Saharan Africa

Personalised Pulmonary Rehabilitation: Harnessing the power of Cardiopulmonary Exercise Testing (CPET)

Rehabilitation

Improving care for ageing patients with chronic respiratory disease

Identification of novel therapeutic targets for TDP-43 proteinopathies

Neurodegeneration

Improving therapies for neurodegenerative diseases

Commensal Fungi in the Lung: Innocent Bystanders or Pathogenic Orchestrators of Severe Asthma?

Clinical mycology

Investigating the relationship between the lung microbiome and severe asthma