Tom's Translational Fellowship research harnesses the power of human induced pluripotent stem cells (iPSCs) coupled with genetic risk to provide complex in vitro models of microglia and organoids that enable him to study the phenotypic consequences of defined risk. He uses a multidisciplinary approach to identify novel targets and pathways that can be therapeutically targeted using strategies including drug repurposing that have the potential to provide rapid translation of findings to the clinic.
Research projects that Tom has been involved in
Neurodegeneration
Understanding the brain’s immune cells to help develop treatments for people with Alzheimer’s disease.
Diabetes
Exploring the role of insulin and islet protection factors released from stem cell derived neural cells to help improve treatment for diabetes
News involving Tom
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