Tom's Translational Fellowship research harnesses the power of human induced pluripotent stem cells (iPSCs) coupled with genetic risk to provide complex in vitro models of microglia and organoids that enable him to study the phenotypic consequences of defined risk. He uses a multidisciplinary approach to identify novel targets and pathways that can be therapeutically targeted using strategies including drug repurposing that have the potential to provide rapid translation of findings to the clinic.